Use of codeine-analgesics, nonsteroidal anti-inflammatory drugs, tricyclic antidepressants, long-acting benzodiazepines, and first generation antihistamines decreased significantly, while use of short-acting benzodiazepines, z-hypnotics, statins, and anti-dementia drugs increased significantly. Use of any single substances to avoid increased from 36.8% in 1997 to 39.5% in 2011 (p = 0.002), use of any combinations to avoid from 16.3% to 27.0% (p < 0.001), and use of any deprescribing items from 46.0% to 55.3% (p < 0.001). The mean overall number of drugs per patient increased from 4.7 in 1997 to 6.9 in 2011 (p < 0.001). We established Pearsons r for correlations between numbers of drugs and PIMs.Īltogether, 4373 patients (mean age 85.7 years, 73.5% women) were included. Associations between sample and use of PIMs were examined by logistic regression, adjusted for age, gender, and ward. PIMs were analyzed according to the Norwegian General Practice-Nursing Home criteria (NORGEP-NH), use of single substances to avoid, combinations to avoid, and deprescribing items.
Patients aged ≥70 years were included from three cross-sectional studies conducted in 1997, 20. The aim of this study was to examine trends in potentially inappropriate medication (PIM) prescribing in Norwegian nursing homes.
